The Stress, Adrenaline, Insuline, Hormone Connection
Adrenaline caused a dose-dependent inhibition (EC50 = nM) of insulin Relationship, Drug; Epinephrine/pharmacology*; Female; Insulin/metabolism*. Hormones released in times of acute stress, such as adrenaline, stop the release of insulin, leading to higher blood glucose levels to help cope with the stressful. Hormones that work against the action of insulin, raising blood glucose hormones are glucagon, epinephrine (also known as adrenaline).
Emotional stress fear, anxiety, anger, excitement, tension and physiological stress illness, pain, infection, injury cause the body to secrete stress hormones into the bloodstream. For those without diabetes, the stress-induced blood sugar rise is followed by an increase in insulin secretion, so the blood sugar rise is modest and temporary.
Adrenaline & Glucose
For those of us with diabetes, however, stress can cause a significant and prolonged increase in the blood sugar level. Anxious moments and nerve-racking situations happen to all of us. From speaking in public to test-taking to a simple visit to the doctor or dentist, many events elicit a stress hormone response that causes, among other things, a sharp blood sugar rise. I once experienced another dramatic blood sugar rise when I was late for an important meeting, hit a pothole and got a flat tire, then discovered that the spare tire was also flat.
Of course, different events cause different responses in different people. What causes a great deal of anxiety for you might have no effect on someone else.
The key is to look for patterns. Is there something that causes a consistent blood sugar response in a given situation? It can be helpful to record the causes of your high blood sugars in your written records, and then tally the causes to determine whether specific situations account for a large number of high readings.
One of my clients did this and found that high blood sugars were occurring every time he watched a horror movie on TV or saw one at the movies. Apparently, the stress hormone response to the sudden appearances of the knife-wielding maniac was driving his blood sugar up.
Many anxious moments occur spontaneously. However, some can be predicted. And if you can predict it, you can prevent it. Kirstin Hendrickson Sugar cube Image: Humans ingest glucose in several forms and use the molecule to provide energy to cells.
Table sugar and starch are both sources of glucose. Adrenaline, a hormone released by the adrenal glands, can affect blood concentrations of glucose.
Relationship Adrenaline, also known by the scientific name epinephrine, is a hormone that's responsible for the "fight or flight" response that occurs under conditions of excitement or imminent danger. One of the major effects of adrenaline is to increase the power of muscular contraction, in skeletal muscle and in the heart.
In the case of the heart muscle, adrenaline also increases the heart rate, explains Dr.
Adrenaline inhibition of insulin release: role of cyclic AMP.
Lauralee Sherwood in her text, "Human Physiology. Significance Glucose is found many places in the body. The significance of adrenaline relative to glucose is that it causes increased body demand for glucose so that muscles have plenty of glucose available to them in the presence of the stimulating influence of adrenaline. Generally, the amount of glucose in the bloodstream isn't sufficient to provide the necessary fuel for the muscles under conditions in which the adrenal glands have released adrenaline, explains Dr.
- How Stress Hormones Raise Blood Sugar
- Adrenaline inhibition of insulin release: role of cyclic AMP.
- You and Your Hormones