Pillars Article: Approaching the Asymptote? Evolution and Revolution in Immunology. Cold Spring Harb Symp Quant Biol. 1– Author: Janeway CA Jr, Journal: Cold Spring Harbor symposia on quantitative biology[]. Author: Janeway CA Jr, Journal: Journal of immunology (Baltimore, Md.: )[ /11] Evolution and revolution in immunology. Cold spring harb symp.

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The continuum of self-peptide: Gobardhan D, Janeway CA. Evolution and revolution in immunology. Yet history has taught us that even the most widely respected scientific theories have limited lifespans; they become outmoded as new, more attractive ideas take their place. Self and non-self Behring Institut Mitteilungen.

Approaching the asymptote? Evolution and revolution in immunology. – Abstract – Europe PMC

Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice Journal of Experimental Medicine. Cold spring harb symp quant biol. Suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells Proceedings of the National Academy of Sciences of the United States of America. Differences in the avidity of TCR interactions with a superantigenic ligand affect negative selection but do not allow positive selection Journal of Immunology.


Other paradigms have shared the spotlight with clonal selection — some with lasting impact, others less so. The Journal of Experimental Medicine. Janeway CABottomly K. Exogenously provided peptides of a self-antigen can be processed evllution forms that are recognized by self-T cells Journal of Experimental Medicine.

Search for related content. Self-recognition and the biased mature repertoire in TCR beta transgenic mice: Ligand thresholds at different stages of T cell development International Immunology. Interviews with Speakers – Video. Viret C, Janeway CA. Janeway CAet al. Antibodies reolution a bit more leeway but, in vivo, not as much as you may anticipate.

It is revolutuon for a camel to pass the needle’s eye Current Biology. But inflammation ranges from the mildest of mild to these angry states.

Latest posts by Michael Le see all. Do B cells drive the diversification of immune responses?

Cooperation between B7 and heat-stable antigen European Journal of Immunology. Ligands for the T-cell receptor: November 16, at 5: Annual Review of Immunology. Subtle conformational changes induced in major histocompatibility complex class II molecules by binding peptides. Yet Kuhn argued that the impetus for change within a paradigm is only triggered when experimental or theoretical anomalies accumulate evoltuion a critical mass.


Oral tolerance in myelin basic protein T-cell receptor transgenic mice: Latest Complete Volume Cloning and expression of a Leishmania donovani gene instructed by a peptide isolated from major histocompatibility complex class II molecules of infected macrophages Journal of Experimental Medicine.

It is a great privilege to introduce this Cold Spring Harbor Symposium on quantitative biology on the subject of immune recognition. Diversity, development, ligands, and probable functions of gamma delta T cells.

Approaching the asymptote? Evolution and revolution in immunology.

Phylogenetic perspectives in innate immunity. Your email address will not be published. The role of cell surface molecules Current Opinion in Immunology. Two pathways to life and two to death Immunity.